Graphically, that means it would shift out (or up) from the old origin, parallel to the old line. A slope of zero is a horizontal flat line. The rest of the fromt yard slopes up from the basement window towards the street. A negative slope that is larger in absolute value (that is, more negative) means a steeper downward tilt to the line. Dig a big deep hole, fill it with crushed stone and cover it with geotechnical filter fabric or add a drain pipe to a lower grade or both. A higher positive slope means a steeper upward tilt to the line, while a smaller positive slope means a flatter upward tilt to the line. These conditions are true whether or not the slope was positive or negative to begin with. When a line has a negative slope the two variables move in opposite directions. Suppose the slope of a line were to decrease. Negative-Slope If a line slopes downward when you move from left to right the line has a negative slope.
Graphically, that means it would get steeper. Suppose the slope of a line were to increase. frequency response may be exacerbated by cascading such amplifiers in series, which is a common technique to increase overall gain. Thus, the slope of a straight line between these two points would be the following: from the altitude of 4,000 meters up to 6,000 meters, the density of the air decreases by approximately 0.1 kilograms/cubic meter for each of the next 1,000 meters. Negative gain slope can be a major limitation for broadband applications which require consistent gain performance across wide frequency ranges. These findings suggest that in addition to a voltage-dependent step associated with Na+ translocation, a second voltage-dependent step that is dependent on external, possibly external K+ binding, participates in the overall reaction mechanism of the Na+/K+ pump.\( \newcommand\) At an extracellular of 1.3 mM, a negative slope was observed at positive potentials. In 90 mM Na+, 5 mM K+ solution, Na+/K+ pump current-voltage curves at negative membrane potentials have a positive slope and can be described by a monotonically increasing sigmoidal function. The occurrence of a negative slope can be explained by the voltage dependence of the apparent affinity for activation of the Na+/K+ pump by external K+, consistent with the existence of an external ion well for K+ binding. The mechanism of the negative slope in the currentlight characteristics of twinstripe lasers is explained by the dependence of a nearfield pattern on the. Similar results are seen in Na(+)- and Ca(2+)-free solutions in the presence of 2 mM Ni2+, an experimental condition designed to prevent Na+/Ca2+ exchange. If external is reduced below 0.5 mM, negative slopes are observed over this entire voltage range. In Na(+)-free solution containing 5 mM K+, Na+/K+ pump current is relatively voltage independent over the potential range from -160 to +40 mV. Reductions in steady-state current (on the order of 700 nA/cm2) produced by 50 microM ouabain or dihydro-ouabain or by K+ removal, therefore, primarily represent current generated by the Na+/K+ pump. If, in addition, the Na+/K+ pump is blocked by ouabain, K(+)-sensitive currents no larger than 50 nA/cm2 remain. All solutions contained 5 mM Ba2+ and 20 mM tetraethylammonium (TEA) to block K+ channels. To investigate the voltage dependence of the Na+/K+ pump, current-voltage relations were determined in prophase-arrested oocytes of Xenopus laevis.
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